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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECT2
All Species:
19.09
Human Site:
T391
Identified Species:
52.5
UniProt:
Q9H8V3
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H8V3
NP_060568.3
883
100051
T391
S
L
L
D
I
S
N
T
P
E
S
S
I
N
Y
Chimpanzee
Pan troglodytes
XP_516880
927
105018
T391
S
L
L
D
I
S
N
T
P
E
S
S
I
N
Y
Rhesus Macaque
Macaca mulatta
XP_001083830
927
105162
T391
S
L
L
D
I
S
N
T
P
E
S
S
I
N
Y
Dog
Lupus familis
XP_850841
883
100205
T391
S
L
L
D
I
S
N
T
P
E
S
S
I
N
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q07139
738
83667
A282
Q
S
A
R
W
Q
V
A
K
E
L
Y
Q
T
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506512
776
87137
R320
S
A
R
W
Q
V
A
R
E
L
Y
Q
T
E
S
Chicken
Gallus gallus
XP_422790
883
99425
T391
S
L
L
D
I
S
N
T
P
E
S
S
T
T
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396514
877
98296
R377
A
V
N
T
D
S
S
R
K
N
L
S
P
R
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781936
868
97771
S376
S
C
M
S
I
S
A
S
S
I
L
D
C
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
92
94.7
N.A.
78.8
N.A.
N.A.
73.1
83.2
N.A.
N.A.
N.A.
N.A.
40.7
N.A.
41.6
Protein Similarity:
100
94.3
93.7
98.3
N.A.
81.3
N.A.
N.A.
79.2
91.6
N.A.
N.A.
N.A.
N.A.
60.5
N.A.
61.3
P-Site Identity:
100
100
100
100
N.A.
6.6
N.A.
N.A.
6.6
80
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
6.6
N.A.
N.A.
6.6
80
N.A.
N.A.
N.A.
N.A.
40
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
12
0
0
0
23
12
0
0
0
0
0
0
0
% A
% Cys:
0
12
0
0
0
0
0
0
0
0
0
0
12
0
0
% C
% Asp:
0
0
0
56
12
0
0
0
0
0
0
12
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
12
67
0
0
0
12
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% H
% Ile:
0
0
0
0
67
0
0
0
0
12
0
0
45
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
23
0
0
0
0
0
0
% K
% Leu:
0
56
56
0
0
0
0
0
0
12
34
0
0
0
0
% L
% Met:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
12
0
0
0
56
0
0
12
0
0
0
45
12
% N
% Pro:
0
0
0
0
0
0
0
0
56
0
0
0
12
0
0
% P
% Gln:
12
0
0
0
12
12
0
0
0
0
0
12
12
0
12
% Q
% Arg:
0
0
12
12
0
0
0
23
0
0
0
0
0
12
0
% R
% Ser:
78
12
0
12
0
78
12
12
12
0
56
67
0
12
12
% S
% Thr:
0
0
0
12
0
0
0
56
0
0
0
0
23
23
0
% T
% Val:
0
12
0
0
0
12
12
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
12
12
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
12
12
0
0
45
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _